Saturday 25 August 2012

HSP Research - Updated Numbers

OK, so I've done some similar number crunching on the revised set of data as mentioned earlier in the month.

The search adds 553 papers to the 589 that were there before (there are 20 papers in the search where information doesn't appear to be complete, so I'm not including those for now)

The analyses were papers per year - which I've now graphed:


Number of papers per journal. This time I've restricted it to the journals where there have been at least 10 papers published, including "translations" to the full journal titles:


Number of Papers Per Journal
Journal Title Papers Most Recent
Neurology 66 2010
Journal of Neurology, Neurosurgery, and Psychiatry 47 2012
Journal of the Neurological Sciences 36 2012
neurogenetics 34 2012
American Journal of Human Genetics 33 2012
Archives of Neurology 30 2012
Journal of Neurology 29 2012
Human Molecular Genetics 28 2012
Journal of Medical Genetics 28 2009
Brain 26 2010
Rinsho Shinkeigaku (Clinical Neurology) 24 2011
Annals of Neurology 23 2010
European Journal of Neurology 22 2012
Clinical Genetics 22 2012
American Journal of Medical Genetics 21 2002
Movement Disorders 17 2011
Acta Neurologica Scandinavica 16 2009
European Journal of Human Genetics 15 2012
Human Mutation 14 2011
Human Genetics 14 2010
Brain and Nerve / No to Shinkei 12 2003
Neuromuscular Disorders 10 2009

These additional papers add more names to the researchers list, there now being over 4,400 researchers. The number of authors with more than 10 papers published goes up from 39 to 64. This list now looks like this:


Authors of at least 10 papers
Author Papers  1st Yr Last Yr Papers 1st Auth
Brice A 47 1996 2012
Stevanin G 38 1995 2012 4
Fink JK 29 1995 2010 13
Reid E 27 1997 2012 11
Durr A 26 2000 2012 1
Hazan J 23 1993 2010 4
Crosby AH 22 2001 2010 1
Schöls L 22 2002 2012
Dürr A 21 1994 2009 2
Rouleau GA 20 1989 2012
Fontaine B 20 1994 2010 2
Blackstone C 19 2003 2012 2
Santorelli FM 19 2000 2011 1
Klebe S 18 2004 2012 6
Hedera P 18 1999 2011 10
Schüle R 17 2006 2012 6
Auer-Grumbach M 17 1999 2012 1
Pericak-Vance MA 16 1994 2012
Beetz C 16 2004 2012 7
Warner TT 16 2001 2011 1
Nielsen JE 15 1997 2011 4
Bernardi G 15 1993 2012
Tessa A 15 2000 2011 2
Klimpe S 15 2002 2012 2
Rugarli EI 15 2002 2012 1
Kawarai T 14 2002 2011
Depienne C 14 2006 2012 4
Forlani S 14 2006 2011
Hutchinson M 14 1997 2009
Proukakis C 14 2002 2011 4
Orlacchio A 14 2002 2011 9
Casari G 13 1998 2009 2
Weissenbach J 13 1993 2007
Elleuch N 13 2006 2010 2
Deufel T 12 2000 2009
Paternotte C 12 1996 2007 1
Patton MA 12 2001 2010
Boukhris A 12 2007 2011 4
Rainier S 12 1998 2008 5
Sperfeld AD 12 2004 2010 3
Patel H 12 2001 2008 3
Coutinho P 11 1996 2012 1
Bruyn RP 11 1990 2009 6
Bouslam N 11 2005 2007 2
De Jonghe P 11 1996 2012 1
Bertini E 11 1998 2011 1
Martinuzzi A 11 2003 2012
Feki I 11 2000 2011 1
Filla A 11 1998 2010
Kassubek J 11 2004 2012 1
De Michele G 11 1998 2011 1
Shen L 11 2004 2011
Azzedine H 10 2000 2012
Bassi MT 10 1999 2012
Tang BS 10 2001 2011 1
Tallaksen CM 10 2001 2010 2
Ruberg M 10 2003 2009
Iwabuchi K 10 1990 2008 7
Patrono C 10 2000 2010 2
Kobayashi H 10 1995 2003 3
Burgunder JM 10 1996 2010 1
Zatz M 10 1976 2010 1
Goizet C 10 2006 2012 4
Prud'homme JF 10 1996 2007


The top three most published authors remain the same as in the first set of results - A Brice, G Stevanin and JK Fink, but there are other authors appearing in the updated "top ten". I believe that  "Dürr A" should be "Dürr A" which I think is the same person as "Durr A", which would have been first last time, and equal first this time. Another avenue of data cleansing opens....

The latest search is this: http://www.ncbi.nlm.nih.gov/pubmed?term=((hereditary%20OR%20familial)%20AND%20%22spastic%20paraplegia%22)%20or%20%22strumpell%20lorrain%22. There is only one paper which was in my first search which was not returned in this later search. I'll leave the why of this for another day.

Saturday 11 August 2012

Updated search results - more papers!

Having started to look into the PubMed results a bit more, I wondered if I could find any references to those original Strumpell and Lorrain papers, and started searching around for them.

No joy, but I did manage to find some earlier papers on HSP/FSP, and I realise that the search I was using is limited.

So, the previous search: http://www.ncbi.nlm.nih.gov/pubmed?term=%22Spastic%20Paraplegia,%20Hereditary%22[Majr] now reveals 599, suggesting another 10 papers have been added. The earliest paper is from 1978, which I now realise means theres not far off 100 years worth of potentially published research missing.

So, I've spent a while messing about trying to get better results. It seems there's a balance to be struck. For example, a simple search on spastic paraplegia reveals some 17,000 results, and thats because the simple search brings back every paper with both words somewhere in the entry.

A better search result happens when you put quotes round "spastic paraplegia", giving some 1500 results. If the term "strumpell lorrain" is added you add a few more, including some back to the late 1800's.

However, its clear from browsing some of the abstracts that not all of these appear to be obviously relevant, so I added in the words hereditary and familial to the search. This gives a total of 1162 papers. Search here: http://www.ncbi.nlm.nih.gov/pubmed?term=((hereditary%20OR%20familial)%20AND%20%22spastic%20paraplegia%22)%20or%20%22strumpell%20lorrain%22. Earliest paper - 1946.

Next stage - to update my previous analyses of data and find out the most popular journals, years of research and published authors. Note - I have a feeling that this will end up being an iterative process, so I think I'll post this data on a page rather than in a post.