HSP Research - Updated Numbers

OK, so I've done some similar number crunching on the revised set of data as mentioned earlier in the month.

The search adds 553 papers to the 589 that were there before (there are 20 papers in the search where information doesn't appear to be complete, so I'm not including those for now)

The analyses were papers per year - which I've now graphed:

Number of papers per journal. This time I've restricted it to the journals where there have been at least 10 papers published, including "translations" to the full journal titles:

Number of Papers Per Journal

Journal Title	Papers	Most Recent
Neurology	66	2010
Journal of Neurology, Neurosurgery, and Psychiatry	47	2012
Journal of the Neurological Sciences	36	2012
neurogenetics	34	2012
American Journal of Human Genetics	33	2012
Archives of Neurology	30	2012
Journal of Neurology	29	2012
Human Molecular Genetics	28	2012
Journal of Medical Genetics	28	2009
Brain	26	2010
Rinsho Shinkeigaku (Clinical Neurology)	24	2011
Annals of Neurology	23	2010
European Journal of Neurology	22	2012
Clinical Genetics	22	2012
American Journal of Medical Genetics	21	2002
Movement Disorders	17	2011
Acta Neurologica Scandinavica	16	2009
European Journal of Human Genetics	15	2012
Human Mutation	14	2011
Human Genetics	14	2010
Brain and Nerve / No to Shinkei	12	2003
Neuromuscular Disorders	10	2009

These additional papers add more names to the researchers list, there now being over 4,400 researchers. The number of authors with more than 10 papers published goes up from 39 to 64. This list now looks like this:

Authors of at least 10 papers

Author	Papers	1st Yr	Last Yr	Papers 1st Auth
Brice A	47	1996	2012
Stevanin G	38	1995	2012	4
Fink JK	29	1995	2010	13
Reid E	27	1997	2012	11
Durr A	26	2000	2012	1
Hazan J	23	1993	2010	4
Crosby AH	22	2001	2010	1
Schöls L	22	2002	2012
Dürr A	21	1994	2009	2
Rouleau GA	20	1989	2012
Fontaine B	20	1994	2010	2
Blackstone C	19	2003	2012	2
Santorelli FM	19	2000	2011	1
Klebe S	18	2004	2012	6
Hedera P	18	1999	2011	10
Schüle R	17	2006	2012	6
Auer-Grumbach M	17	1999	2012	1
Pericak-Vance MA	16	1994	2012
Beetz C	16	2004	2012	7
Warner TT	16	2001	2011	1
Nielsen JE	15	1997	2011	4
Bernardi G	15	1993	2012
Tessa A	15	2000	2011	2
Klimpe S	15	2002	2012	2
Rugarli EI	15	2002	2012	1
Kawarai T	14	2002	2011
Depienne C	14	2006	2012	4
Forlani S	14	2006	2011
Hutchinson M	14	1997	2009
Proukakis C	14	2002	2011	4
Orlacchio A	14	2002	2011	9
Casari G	13	1998	2009	2
Weissenbach J	13	1993	2007
Elleuch N	13	2006	2010	2
Deufel T	12	2000	2009
Paternotte C	12	1996	2007	1
Patton MA	12	2001	2010
Boukhris A	12	2007	2011	4
Rainier S	12	1998	2008	5
Sperfeld AD	12	2004	2010	3
Patel H	12	2001	2008	3
Coutinho P	11	1996	2012	1
Bruyn RP	11	1990	2009	6
Bouslam N	11	2005	2007	2
De Jonghe P	11	1996	2012	1
Bertini E	11	1998	2011	1
Martinuzzi A	11	2003	2012
Feki I	11	2000	2011	1
Filla A	11	1998	2010
Kassubek J	11	2004	2012	1
De Michele G	11	1998	2011	1
Shen L	11	2004	2011
Azzedine H	10	2000	2012
Bassi MT	10	1999	2012
Tang BS	10	2001	2011	1
Tallaksen CM	10	2001	2010	2
Ruberg M	10	2003	2009
Iwabuchi K	10	1990	2008	7
Patrono C	10	2000	2010	2
Kobayashi H	10	1995	2003	3
Burgunder JM	10	1996	2010	1
Zatz M	10	1976	2010	1
Goizet C	10	2006	2012	4
Prud'homme JF	10	1996	2007

The top three most published authors remain the same as in the first set of results - A Brice, G Stevanin and JK Fink, but there are other authors appearing in the updated "top ten". I believe that  "Dürr A" should be "Dürr A" which I think is the same person as "Durr A", which would have been first last time, and equal first this time. Another avenue of data cleansing opens....

The latest search is this: http://www.ncbi.nlm.nih.gov/pubmed?term=((hereditary%20OR%20familial)%20AND%20%22spastic%20paraplegia%22)%20or%20%22strumpell%20lorrain%22. There is only one paper which was in my first search which was not returned in this later search. I'll leave the why of this for another day.

Updated search results - more papers!

Having started to look into the PubMed results a bit more, I wondered if I could find any references to those original Strumpell and Lorrain papers, and started searching around for them.

No joy, but I did manage to find some earlier papers on HSP/FSP, and I realise that the search I was using is limited.

So, the previous search: http://www.ncbi.nlm.nih.gov/pubmed?term=%22Spastic%20Paraplegia,%20Hereditary%22[Majr] now reveals 599, suggesting another 10 papers have been added. The earliest paper is from 1978, which I now realise means theres not far off 100 years worth of potentially published research missing.

So, I've spent a while messing about trying to get better results. It seems there's a balance to be struck. For example, a simple search on spastic paraplegia reveals some 17,000 results, and thats because the simple search brings back every paper with both words somewhere in the entry.

A better search result happens when you put quotes round "spastic paraplegia", giving some 1500 results. If the term "strumpell lorrain" is added you add a few more, including some back to the late 1800's.

However, its clear from browsing some of the abstracts that not all of these appear to be obviously relevant, so I added in the words hereditary and familial to the search. This gives a total of 1162 papers. Search here: http://www.ncbi.nlm.nih.gov/pubmed?term=((hereditary%20OR%20familial)%20AND%20%22spastic%20paraplegia%22)%20or%20%22strumpell%20lorrain%22. Earliest paper - 1946.

Next stage - to update my previous analyses of data and find out the most popular journals, years of research and published authors. Note - I have a feeling that this will end up being an iterative process, so I think I'll post this data on a page rather than in a post.